26, 4, 9
21 consecutive patients with refractory ARDS imaged immediately before VV ECMO cannulation, selected from a larger series for the presence of pulmonary vascular dysfunction (17 with normal biventricular function and 8 with isolated LV dysfunction were excluded before analysis). Overall mortality 57.1%. Acute cor pulmonale in 2 of 21 (9.5%), both of whom died; the remaining 19 had moderate pulmonary dysfunction (systolic pulmonary artery pressure over 40 mmHg or a dilated RV). TAPSE under 16 mm in 10 of 21 (47.6%).
Survivors versus non-survivors: LVEF 56.1 ± 12% versus 46.9 ± 11% (p = 0.02); TAPSE 16.9 ± 3.7 mm versus 13 ± 4.5 mm (p = 0.04); systolic pulmonary artery pressure 47.7 ± 5.8 versus 57 ± 6.7 mmHg.
NUMERICAL DISCREPANCY RECORDED AND NOT CORRECTED: the abstract gives p = 0.02 for the systolic pulmonary artery pressure comparison and the results table gives p = 0.004 for the same comparison. Both are printed in Chapter 26; neither is asserted.
Certainty: very low. The pre-selection makes the percentages uninterpretable as prevalence figures. Only the direction — a worse right heart before cannulation predicts worse outcome after it — is taken.
Read as indexed full-text passages. DOI not independently resolved.