Three major 2025 AKI/RRT trials, summarized in full CCR 11-part format — spanning perioperative AKI prevention, dialysis intensity/liberation strategy, and sodium bicarbonate for severe metabolic acidemia.
BigpAK-2 — Preventive Care Strategy to Reduce AKI After Major SurgeryLIBERATE-D — Conservative Dialysis Strategy and Kidney Function RecoveryBICARICU-2 — Sodium Bicarbonate for Severe Metabolic Acidemia and AKI🦬