Five major 2025 neurocritical care and cardiac-support trials, summarized in full CCR 11-part format — spanning intra-arterial thrombolytic strategies after successful thrombectomy, antiplatelet therapy after IV thrombolysis, cerebral temperature control, and ECMO weaning pharmacology.
PEARL — Intra-Arterial Alteplase After Successful EVTANGEL-TNK — Intra-Arterial Tenecteplase After Successful EVTASSET-IT — Early Tirofiban After IV Thrombolysis for StrokeNEUROTHERM — Effect of Paracetamol on Cerebral TemperatureLEVOECMO — Levosimendan to Facilitate ECMO Weaning🧠