Three major 2026 mechanical ventilation / respiratory support trials, summarized in full CCR 11-part format. Note: this category had fewer confirmed, fully-reported 2026 RCTs than Sepsis — 3 solid trials rather than 5. A 4th candidate (DESIGNATION, driving-pressure-guided PEEP) was published in JAMA 2025 and is excluded here as it predates the 2026 window; happy to add it as a bridging reference if useful.
SOHO — High-Flow vs Standard Oxygen in Acute Hypoxemic Respiratory FailureEITVent — EIT-Guided PEEP and Mortality in ARDSNOTACS — High-Flow Nasal Oxygen After Cardiac Surgery🫁